Sirius Therapeutics is a global clinical-stage biotechnology company dedicated to unlocking the clinical and commercial value of siRNA therapeutics. The Company's goal is to transform the current standard of care for chronic diseases by developing first-in-class and best-in-class siRNA therapeutics for large unmet global medical needs, a strategy underpinned by three mega-blockbuster franchises, proprietary siRNA technology platform (PEPR) and global partnership and capabilities.
Sirius is focused on three mega-blockbuster franchises, targeting coagulation disorders, cardiometabolic diseases, and obesity.
Sirius Therapeutics was founded in 2021 and is a globally integrated biotechnology company with operations in San Diego, USA, and Shanghai, China. The Company's strategic advantage is rooted in a hybrid operational model that seamlessly combines the exceptional early development capacity and cost-efficiency of the Company's China-based team with the global discovery and regulatory expertise of the U.S.-based team.
First patient dosed in SRSD384 Phase 1/2a trial
First patient dosed in SRSD107 Phase 2 trial in CAD/PAD patients
First patient dosed in SRSD216 Phase 2 trial
First patient dosed in SRSD107 Phase 2 trial in Europe
EMA approval for SRSD107 Phase 2 trial in Europe
Multi-target collaboration agreement signed with CRISPR Therapeutics
Series B2 financing: nearly US$50mn raised
FDA clearance of IND for SRSD216 to begin clinical trials in USA
NMPA approval for SRSD216 Phase 1/2a trial in China
Announced data from SRSD107 Phase 1 trial in Australia
First patient in dosed in SRSD107 Phase 1 trial in China
NMPA approval for SRSD107 Phase 1 trial in China
Received IND clearance of SRSD107 by NMPA
First patient dosed in SRSD107 Phase 1 trial in Australia
Completed the FIH of SRSD107 in Australia
Established US site in San Diego
Received IND clearance of SRSD101 by NMPA
Submitted the HRECs in Australia of SRSD107
Completed Series B financing
Submitted the first IND to China NMPA
Established company’s new office in Shanghai,China
Completed Series A financing
Sirius China was officially established
Established US Office in Boston
Sirius US was officially established
2026
2025
2024
2023
2022
2021

Sirius Therapeutics, Inc., all rights reserved
为了更好的呈现效果,移动端请竖屏浏览